operate
verb.
direct or control; projects, businesses, etc.
She is running a relief operation in the Sudan
Synonym: run
verb.
perform as expected when applied
The washing machine won't go unless it's plugged in|Does this old car still run well?|This old radio doesn't work anymore
Synonym: function, go, run, work
verb.
handle and cause to function
do not operate machinery after imbibing alcohol|control the lever
Synonym: control
verb.
perform a movement in military or naval tactics in order to secure an advantage in attack or defense
verb.
keep engaged
engaged the gears
Synonym: mesh, lock, engage
verb.
perform surgery on
The doctors operated on the patient but failed to save his life
Synonym: operate on